A new dimeric secoiridoids derivative, japonicaside E, from the flower buds of Lonicera japonica

Nat Prod Res. 2019 Jan;33(1):53-58. doi: 10.1080/14786419.2018.1431641. Epub 2018 Mar 3.

Abstract

A new dimeric secoiridoids derivative, named japonicaside E, together with six known compounds were isolated from the flower buds of Lonicera japonica. The structures of these compounds were elucidated by the analyses of mass spectrometry and NMR spectroscopy. All compounds were evaluated for anti-inflammatory activity in vitro.

Keywords: PGE; anti-inflammatory; dimeric secoiridoids glucoside; japonicaside E.

MeSH terms

  • Anti-Inflammatory Agents / isolation & purification
  • Anti-Inflammatory Agents / pharmacology
  • Flowers / chemistry
  • Iridoids / isolation & purification*
  • Lonicera / chemistry*
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Molecular Structure

Substances

  • Anti-Inflammatory Agents
  • Iridoids