Perioperative infections after orthopedic surgery are complications that extend the process of treatment and rehabilitation of patients. The multifactor mechanism of their formation has already been defined, which allows effective control of the threat. In addition to the introduction of ever safer surgical techniques, strict epidemic surveillance and acceptable by the body implanted materials, widely prophylactic perioperative antibiotic therapy is applied. The effects of this action are demonstrated in available clinical analyzes, which indicate a reduction in the scale of the threat. When using antibiotics, pay attention to their spectrum of activity and penetrations to the place of the ongoing inflammatory process. On the basis of these parameters, the dose, time and route of administration should be set so that the prophylaxis is fully effective.
Keywords: orthopedic surgery; perioperative antibiotic; prevention.