Visualizing the Human Subcortex Using Ultra-high Field Magnetic Resonance Imaging

Brain Topogr. 2018 Jul;31(4):513-545. doi: 10.1007/s10548-018-0638-7. Epub 2018 Mar 2.

Abstract

With the recent increased availability of ultra-high field (UHF) magnetic resonance imaging (MRI), substantial progress has been made in visualizing the human brain, which can now be done in extraordinary detail. This review provides an extensive overview of the use of UHF MRI in visualizing the human subcortex for both healthy and patient populations. The high inter-subject variability in size and location of subcortical structures limits the usability of atlases in the midbrain. Fortunately, the combined results of this review indicate that a large number of subcortical areas can be visualized in individual space using UHF MRI. Current limitations and potential solutions of UHF MRI for visualizing the subcortex are also discussed.

Keywords: Magnetic resonance imaging; Review; Subcortex; Ultra-high field.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Brain / diagnostic imaging*
  • Humans
  • Magnetic Resonance Imaging / methods*