Capturing a Long Look at Our Genetic Library

Julien Lagarde; Rory Johnson

doi:10.1016/j.cels.2018.02.003

Capturing a Long Look at Our Genetic Library

Cell Syst. 2018 Feb 28;6(2):153-155. doi: 10.1016/j.cels.2018.02.003.

Authors

Julien Lagarde¹, Rory Johnson²

Affiliations

¹ Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Catalonia, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Catalonia, Spain.
² Department of Medical Oncology, Inselspital, University Hospital and University of Bern, 3010 Bern, Switzerland; Department of Biomedical Research (DBMR), University of Bern, 3008 Bern, Switzerland. Electronic address: rory.johnson@dbmr.unibe.ch.

PMID: 29494803
DOI: 10.1016/j.cels.2018.02.003

Abstract

Long-read sequencing, coupled to cDNA capture, provides an unrivaled view of the transcriptome of chromosome 21, revealing surprises about the splicing of long noncoding RNAs.

Publication types

Comment

MeSH terms

Alternative Splicing*
Exons
Gene Library
High-Throughput Nucleotide Sequencing*
Sequence Analysis, RNA

Grants and funding

U41 HG007234/HG/NHGRI NIH HHS/United States