Assessment of sella turcica area and skeletal maturation patterns of children with unilateral cleft lip and palate

Orthod Craniofac Res. 2018 May;21(2):78-83. doi: 10.1111/ocr.12219. Epub 2018 Mar 1.

Abstract

Objectives: The aim of this case-control study was to assess sella turcica area and skeletal maturity in children with unilateral cleft lip and palate (UCLP) and compare with those of non-cleft children.

Setting and sample population: A total of 85 UCLP patients aged 7.5-17.08 years (Group 1: age 7-11 years, Group 2: age 11-14 years and Group 3: age 14-18 years) were compared with 85 control subjects without clefts who were divided into similar age groups.

Materials and methods: Hand-wrist radiographs and cervical vertebra maturation stages (CVMS) were used to evaluate growth. Lateral cephalograms were traced, and reference points of sella were determined. Sella turcica area was measured using a digital planimeter.

Results: Comparison of overall growth on hand-wrist radiographs revealed no significant difference between cleft and non-cleft subjects. However, according to the chronological age groups, Group 1-UCLP showed statistically significant delay in skeletal maturation when compared with the age-matched control subjects (P = .05). This difference was due to the delay among male subjects (P = .05). As for CVMS, more significant maturation delay was observed in Group 1-UCLP (P = .001) and was attributable to both male and female subjects (P = .05). Comparison of sella turcica area showed no significant difference between UCLP patients and controls.

Conclusion: Although children with CLP showed significant delay in growth when they are younger compared with the non-cleft children, sella turcica area measurements were similar for individuals in both groups.

Keywords: cleft lip and palate; sella Turcica; skeletal maturation.

MeSH terms

  • Adolescent
  • Age Determination by Skeleton / methods
  • Case-Control Studies
  • Child
  • Cleft Lip / physiopathology*
  • Cleft Palate / physiopathology*
  • Growth / physiology*
  • Hand / diagnostic imaging
  • Humans
  • Radiography
  • Sella Turcica / growth & development*
  • Wrist / diagnostic imaging