[The choice of diagnostic modality for acute pulmonary embolism]

Ugeskr Laeger. 2018 Feb 19;180(8):V05170391.
[Article in Danish]

Abstract

The diagnosis of pulmonary embolism (PE) relies on clinical assessment, D-dimer test and diagnostic imaging. Modern CT pulmonary angiography (CTPA), ventilation/perfusion single-photon emission computed tomography (SPECT) and SPECT/CT are rather equal in terms of sensitivity, specificity and inconclusive results for the diagnosis of PE, outper-forming planar lung scintigraphy. Furthermore, SPECT/CT and CTPA can both provide important information regarding differential diagnoses. Thus, the choice of primary diag-nostic modality relies on local expertise, availability and special circumstances like radiation dose, contraindications and the clinical urgency.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Computed Tomography Angiography / adverse effects
  • Computed Tomography Angiography / standards
  • Contraindications, Procedure
  • Fibrin Fibrinogen Degradation Products / metabolism
  • Humans
  • Pulmonary Embolism / blood
  • Pulmonary Embolism / diagnosis
  • Pulmonary Embolism / diagnostic imaging*
  • Radiation Dosage
  • Radionuclide Imaging / adverse effects
  • Radionuclide Imaging / standards
  • Sensitivity and Specificity
  • Single Photon Emission Computed Tomography Computed Tomography / adverse effects
  • Single Photon Emission Computed Tomography Computed Tomography / standards
  • Tomography, Emission-Computed, Single-Photon / adverse effects
  • Tomography, Emission-Computed, Single-Photon / standards

Substances

  • Fibrin Fibrinogen Degradation Products