Was the calf circumference associated with serum vitamin D level in obesity and non-obesity adults

Chen-Jung Wu; Tung-Wei Kao; Chia-Kuang Tsai; Yaw-Wen Chang; Tao-Chun Peng; Hui-Fang Yang; Li-Wei Wu; Wei-Liang Chen

doi:10.1016/j.cca.2018.02.028

Was the calf circumference associated with serum vitamin D level in obesity and non-obesity adults

Clin Chim Acta. 2018 Jun:481:42-48. doi: 10.1016/j.cca.2018.02.028. Epub 2018 Feb 23.

Authors

Chen-Jung Wu¹, Tung-Wei Kao², Chia-Kuang Tsai³, Yaw-Wen Chang⁴, Tao-Chun Peng⁴, Hui-Fang Yang⁴, Li-Wei Wu⁴, Wei-Liang Chen⁵

Affiliations

¹ Division of Family Medicine, Department of Community Medicine, Taoyuan Armed Forces General Hospital, Taoyuan, Taiwan, Republic of China; Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital, Taipei, Taiwan, Republic of China; School of Medicine, National Defense Medical Center, Taipei, Taiwan, Republic of China.
² Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital, Taipei, Taiwan, Republic of China; Division of Geriatric Medicine, Department of Family and Community Medicine, Tri-Service General Hospital, Taipei, Taiwan, Republic of China; Graduate Institute of Clinical Medical, College of Medicine, National Taiwan University, Taipei, Taiwan, Republic of China; School of Medicine, National Defense Medical Center, Taipei, Taiwan, Republic of China.
³ Department of Neurology, Tri-Service General Hospital, Taipei, Taiwan, Republic of China; School of Medicine, National Defense Medical Center, Taipei, Taiwan, Republic of China.
⁴ Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital, Taipei, Taiwan, Republic of China; Division of Geriatric Medicine, Department of Family and Community Medicine, Tri-Service General Hospital, Taipei, Taiwan, Republic of China; School of Medicine, National Defense Medical Center, Taipei, Taiwan, Republic of China.
⁵ Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital, Taipei, Taiwan, Republic of China; Division of Geriatric Medicine, Department of Family and Community Medicine, Tri-Service General Hospital, Taipei, Taiwan, Republic of China; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan, Republic of China; School of Medicine, National Defense Medical Center, Taipei, Taiwan, Republic of China. Electronic address: weiliang0508@gmail.com.

PMID: 29481775
DOI: 10.1016/j.cca.2018.02.028

Abstract

Purposed: This study examined the associations between 25-hydroxyvitamin D [25(OH)D] and common anthropometric parameters.

Methods: The data were derived from the National Health and Nutrition Examination Survey from 2001 through 2004. We divided all subjects into two groups with a cut-off point for body mass index set at 30. The primary outcome was the potential relationship between the anthropometric parameters and 25(OH)D status.

Results: A positive association was found between the 25(OH)D levels and calf circumference (CC) in all of the designed models (P < 0.001). The adjusted β coefficient of the 25(OH)D levels for the CC was 0.542 (95% confidence intervals (CI), 0.376-0.708, P < 0.001) after adjusting for all covariates. An increasing linear tendency for 25(OH)D was present in non-obese participants. Additionally, subjects in the higher tertiles of CC tended to have higher 25(OH)D levels with a significant correlation (P for trend <0.001).

Conclusion: A positive association between 25(OH)D concentration and CC in non-obese individuals was observed.

Keywords: Anthropometric parameters; Obesity; Skeletal muscle; Vitamin D.

MeSH terms

Adult
Anthropometry*
Female
Humans
Male
Middle Aged
Obesity / blood*
Obesity / diagnosis*
Vitamin D / analogs & derivatives*
Vitamin D / blood

Substances

Vitamin D
25-hydroxyvitamin D