Pregnancy and End-Stage Renal Disease

Jessica Tangren; Molly Nadel; Michelle A Hladunewich

doi:10.1159/000485157

Pregnancy and End-Stage Renal Disease

Blood Purif. 2018;45(1-3):194-200. doi: 10.1159/000485157. Epub 2018 Jan 26.

Authors

Jessica Tangren¹, Molly Nadel¹, Michelle A Hladunewich²

Affiliations

¹ Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Harvard University, Boston, Massachusetts, USA.
² Division of Nephrology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

PMID: 29478065
DOI: 10.1159/000485157

Abstract

Pregnancy is uncommon in women with end-stage renal disease (ESRD). Fertility rates are low in women on dialysis, and physicians still frequently counsel women with ESRD against pregnancy. Advancements in the delivery of dialysis and obstetric care have led to improved live birth rates in women on dialysis, so pregnancy for young women with ESRD is now more feasible and safer. However, these pregnancies remain high-risk for both maternal and fetal complications, necessitating experienced multidisciplinary care. In this article, we review fertility issues in women with ESRD, discuss pregnancy outcomes in women on dialysis, and provide an approach for management of pregnant women with ESRD.

Keywords: End-stage renal disease; Intensive hemodialysis; Pregnancy.

Publication types

Review

MeSH terms

Female
Humans
Kidney Failure, Chronic* / diagnosis
Kidney Failure, Chronic* / physiopathology
Kidney Failure, Chronic* / therapy
Pregnancy
Pregnancy Complications* / diagnosis
Pregnancy Complications* / physiopathology
Pregnancy Complications* / therapy
Pregnancy Outcome*
Renal Dialysis*