Modulation of defensive airway reflexes during continuous positive airway pressure in the rabbit

Iulia Ioan; Bruno Demoulin; Anne-Laure Leblanc; Cyril Schweitzer; François Marchal; Laurent Foucaud; Silvia Demoulin-Alexikova

doi:10.1016/j.resp.2018.02.011

Modulation of defensive airway reflexes during continuous positive airway pressure in the rabbit

Respir Physiol Neurobiol. 2018 Nov:257:87-92. doi: 10.1016/j.resp.2018.02.011. Epub 2018 Feb 21.

Authors

Iulia Ioan¹, Bruno Demoulin¹, Anne-Laure Leblanc¹, Cyril Schweitzer¹, François Marchal¹, Laurent Foucaud¹, Silvia Demoulin-Alexikova²

Affiliations

¹ EA 3450 DevAH - Laboratory of Physiology, Faculty of Medicine, Université de Lorraine, Vandœuvre-lès-Nancy, France.
² EA 3450 DevAH - Laboratory of Physiology, Faculty of Medicine, Université de Lorraine, Vandœuvre-lès-Nancy, France. Electronic address: silvia.demoulin-alexikova@univ-lorraine.fr.

PMID: 29474952
DOI: 10.1016/j.resp.2018.02.011

Abstract

Lung hyperinflation may alter the pattern of ventilatory reflexes in chronic respiratory disorders. The aim of the study was to test the effect of continuous positive airway pressure (CPAP) on ventilatory responses to mechanical stimulation of the trachea.

Keywords: Chronic cough; Continuous positive airway pressure; Cough reflex; Expiration reflex; Expiratory flow limitation; Expiratory muscle; Lung hyperinflation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Continuous Positive Airway Pressure*
Cough / physiopathology*
Exhalation / physiology
Rabbits
Reflex* / physiology
Tidal Volume
Trachea / physiopathology