Abstract
In this issue of Blood, Aschemeyer et al found that hepcidin bound to the central cavity of ferroportin (Fpn) and occluded its iron export activity, thereby revealing a previously unrecognized mechanism for Fpn regulation.
MeSH terms
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Binding Sites
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Cation Transport Proteins*
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Hepcidins*
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Protein Domains
Substances
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Cation Transport Proteins
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Hepcidins
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metal transporting protein 1