Adolescence and the next generation

George C Patton; Craig A Olsson; Vegard Skirbekk; Richard Saffery; Mary E Wlodek; Peter S Azzopardi; Marcin Stonawski; Bruce Rasmussen; Elizabeth Spry; Kate Francis; Zulfiqar A Bhutta; Nicholas J Kassebaum; Ali H Mokdad; Christopher J L Murray; Andrew M Prentice; Nicola Reavley; Peter Sheehan; Kim Sweeny; Russell M Viner; Susan M Sawyer

doi:10.1038/nature25759

Adolescence and the next generation

Nature. 2018 Feb 21;554(7693):458-466. doi: 10.1038/nature25759.

Authors

George C Patton^{1

2

3}, Craig A Olsson^{1

2

3

4}, Vegard Skirbekk^{5

6}, Richard Saffery^{1

2}, Mary E Wlodek⁷, Peter S Azzopardi^{1

2

8

9}, Marcin Stonawski^{10

11}, Bruce Rasmussen¹², Elizabeth Spry^{2

3

4}, Kate Francis^{2

3}, Zulfiqar A Bhutta^{13

14}, Nicholas J Kassebaum^{15

16}, Ali H Mokdad¹⁵, Christopher J L Murray¹⁵, Andrew M Prentice^{17

18}, Nicola Reavley¹⁹, Peter Sheehan¹², Kim Sweeny¹², Russell M Viner²⁰, Susan M Sawyer^{1

2

3}

Affiliations

¹ The University of Melbourne, Department of Paediatrics, Faculty of Medicine, Dentistry and Health Sciences, Parkville, Victoria 3010, Australia.
² Murdoch Children's Research Institute, Parkville, Victoria 3052, Australia.
³ Centre for Adolescent Health, Royal Children's Hospital, Parkville, Victoria 3052, Australia.
⁴ Deakin University Geelong, Centre for Social and Early Emotional Development, School of Psychology, Faculty of Health, Geelong, Victoria 3220, Australia.
⁵ Centre for Fertility and Health, Norwegian Institute of Public Health, Nydalen, Oslo 0403, Norway.
⁶ Columbia University, New York, New York 10032, USA.
⁷ The University of Melbourne, Department of Physiology, Parkville, Victoria 3010, Australia.
⁸ Maternal and Child Health Program, International Development Discipline, Burnet Institute, Melbourne, Victoria 3004, Australia.
⁹ Wardliparingga Aboriginal Research Unit, South Australian Health and Medical Research Institute, Adelaide, South Australia 5000, Australia.
¹⁰ Department of Demography, Cracow University of Economics, Cracow 31-510, Poland.
¹¹ European Commission, Joint Research Centre, Centre for Advanced Studies, Ispra, Varese 21027, Italy.
¹² Victoria Institute of Strategic Economic Studies, Victoria University, Melbourne, Victoria 3000, Australia.
¹³ SickKids Centre for Global Child Health, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.
¹⁴ Centre of Excellence in Women and Child Health, Aga Khan University, Karachi 74800, Pakistan.
¹⁵ Institute for Health Metrics and Evaluation, University of Washington, Seattle, Washington 98121, USA.
¹⁶ Division of Pediatric Anesthesiology & Pain Medicine, Seattle Children's Hospital, Seattle, Washington 98105, USA.
¹⁷ MRC Unit The Gambia, Fajara, Gambia.
¹⁸ MRC International Nutrition Group, London School of Hygiene & Tropical Medicine, London WC1E 7HT, UK.
¹⁹ The University of Melbourne, Melbourne School of Population and Global Health, Parkville, Victoria 3010, Australia.
²⁰ UCL Institute of Child Health, University College London, London WC1N 1EH, UK.

PMID: 29469095
DOI: 10.1038/nature25759

Abstract

Adolescent growth and social development shape the early development of offspring from preconception through to the post-partum period through distinct processes in males and females. At a time of great change in the forces shaping adolescence, including the timing of parenthood, investments in today's adolescents, the largest cohort in human history, will yield great dividends for future generations.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adolescent Behavior* / physiology
Adolescent Behavior* / psychology
Adolescent Development / physiology*
Adolescent Health* / statistics & numerical data
Adult
Animals
Child
Cohort Studies
Epigenesis, Genetic
Female
Gametogenesis
Gene-Environment Interaction
Germ Cells / physiology
Housing
Humans
Income
Infant, Newborn
Infant, Small for Gestational Age
Male
Malnutrition / epidemiology
Maternal Age
Maternal Exposure*
Menarche
Parents*
Paternal Age
Paternal Exposure*
Pregnancy
Prenatal Exposure Delayed Effects*
Puberty / physiology
Puberty / psychology
Young Adult

Abstract

Publication types

MeSH terms

Grants and funding