No red blood cell damage and no hemolysis in G6PD-deficient subjects after ingestion of low vicine/convicine Vicia faba seeds

Blood. 2018 Apr 5;131(14):1621-1625. doi: 10.1182/blood-2017-09-806364. Epub 2018 Feb 21.

Authors

Valentina Gallo¹, Oleksii A Skorokhod¹, Luigi Felice Simula², Tiziana Marrocco¹, Elisa Tambini¹, Evelin Schwarzer¹, Pascal Marget³, Gérard Duc³, Paolo Arese¹

Affiliations

¹ Department of Oncology, University of Torino, Torino, Italy.
² Department of Clinical Chemistry, Ospedale Civile, Alghero, Italy; and.
³ Institut National de la Recherche Agronomique, Unité Mixte de Recherche No. 1347-Agroécologie, Institut National Supérieur de Science Agronomique, Dijon, France.

PMID: 29467185
DOI: 10.1182/blood-2017-09-806364

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Child
Child, Preschool
Erythrocytes / metabolism*
Erythrocytes / pathology
Female
Glucosephosphate Dehydrogenase Deficiency / metabolism*
Glucosephosphate Dehydrogenase Deficiency / pathology
Glucosides / chemistry
Glucosides / pharmacology*
Hemolysis / drug effects*
Humans
Male
Pyrimidinones / chemistry
Pyrimidinones / pharmacology*
Seeds / chemistry*
Vicia faba / chemistry*

Substances

Glucosides
Pyrimidinones
vicine