Amino acid racemization and its relation to geochronology and archaeometry

J Sep Sci. 2018 Mar;41(6):1489-1506. doi: 10.1002/jssc.201701506.

Abstract

Amino acid racemization, used as a method of relative and quantitative dating of fossils, evaluates the degree of postmortem conversion of l to d amino acid enantiomers. While extensively utilized, this method has garnered confusion due to controversial age estimates for human fossils in North America in the 1970s. This paper explains the age controversy and aftermath, current chromatographic methods used in research, mathematical calibration models, and a short synopsis of other dating techniques in geochronology and archaeometry.

Keywords: amino acid racemization; archaeology; enantiomeric ratio; geochronological dating.

Publication types

  • Review

MeSH terms

  • Amino Acids / chemistry*
  • Calibration
  • Fossils*
  • Humans
  • Stereoisomerism

Substances

  • Amino Acids