Toxicity of lanthanum oxide nanoparticles to the fungus Moniliella wahieum Y12T isolated from biodiesel

Lin Zhang; Lingyan Zhou; Qing X Li; Hong Liang; Huaming Qin; Stephen Masutani; Brandon Yoza

doi:10.1016/j.chemosphere.2018.02.032

Toxicity of lanthanum oxide nanoparticles to the fungus Moniliella wahieum Y12^T isolated from biodiesel

Chemosphere. 2018 May:199:495-501. doi: 10.1016/j.chemosphere.2018.02.032. Epub 2018 Feb 8.

Authors

Lin Zhang¹, Lingyan Zhou², Qing X Li³, Hong Liang⁴, Huaming Qin⁵, Stephen Masutani⁶, Brandon Yoza⁷

Affiliations

¹ Department of Molecular Biosciences and Bioengineering, University of Hawaii at Manoa, 1955 East West Road, Honolulu, HI 96822 USA; Zhongkai University of Agriculture and Engineering, Guangzhou, Guangdong 510225, China; China Agricultural University, Beijing, 100094, China.
² Department of Molecular Biosciences and Bioengineering, University of Hawaii at Manoa, 1955 East West Road, Honolulu, HI 96822 USA; Zhongkai University of Agriculture and Engineering, Guangzhou, Guangdong 510225, China.
³ Department of Molecular Biosciences and Bioengineering, University of Hawaii at Manoa, 1955 East West Road, Honolulu, HI 96822 USA.
⁴ Zhongkai University of Agriculture and Engineering, Guangzhou, Guangdong 510225, China.
⁵ College of Environmental Science, Jinan University, Guangzhou, Guangdong 510225, China.
⁶ Hawaii Natural Energy Institute, University of Hawaii at Manoa, 1680 East West Rd., Honolulu, HI 96822, USA.
⁷ Hawaii Natural Energy Institute, University of Hawaii at Manoa, 1680 East West Rd., Honolulu, HI 96822, USA. Electronic address: byoza@hawaii.edu.

PMID: 29454172
DOI: 10.1016/j.chemosphere.2018.02.032

Abstract

Moniliella wahieum Y12^T, isolated from biodiesel was used as a model organism to assess the use of lanthanum oxide (La₂O₃) (60-80 nm) and silver oxide (AgO) (10-40 nm) nanoparticles as potential fungal inhibitors. This is the first study to investigate the use of nanoscale La₂O₃ as a eukaryotic bio-inhibitor. The AgO nanoparticles were relatively effective at inhibiting the growth of M. wahieum Y12^T. The half maximal effective concentration (EC₅₀) for AgO was 0.012 mg/mL as compared with 4.63 mg/mL of La₂O₃. Fluorescein diacetate analysis showed that AgO nanoparticles significantly reduced metabolic activity in M. wahieum Y12^T. The results of this study indicated that AgO nanoparticles can be a nonspecific inhibitor for the treatment of M. wahieum Y12^T, a eukaryotic biodiesel contaminant.

Keywords: Biodiesel; Lanthanum oxide; Moniliella wahieum; Nanoparticle; Renewable energy; Silver oxide.

MeSH terms

Biofuels / toxicity*
Fungi / drug effects*
Fungi / growth & development
Fungi / metabolism
Lanthanum / toxicity*
Metal Nanoparticles / toxicity
Nanoparticles / chemistry
Nanoparticles / toxicity
Oxides / toxicity*
Silver Compounds / toxicity

Substances

Biofuels
Oxides
Silver Compounds
lanthanum oxide
Lanthanum
disilver oxide