Assessment of antiplaque effectiveness of chlorhexidine-soaked gauze compared to chlorhexidine mouth rinse: Randomized clinical trial

J Investig Clin Dent. 2018 Aug;9(3):e12328. doi: 10.1111/jicd.12328. Epub 2018 Feb 17.

Abstract

Aim: The aim of the present study was to compare the efficacy of a disposable gauze soaked with chlorhexidine and rolled up on the finger vs chlorhexidine mouth rinse (CM) to maintain oral hygiene.

Methods: In this single-blind, randomized trial, both groups were instructed to brush their teeth and use the 0.12% chlorhexidine intervention twice per day (experimental group: toothbrushing + chlorhexidine-soaked gauze; control group: toothbrushing + mouth rinse). The main outcome was the change in full mouth plaque index scores from baseline to 2 weeks. Secondary outcomes were the patient's appreciation (visual analog scale) and the bleeding index.

Results: The final sample consisted of 60 young patients: 31 in the experimental group and 29 in the control group. After 2 weeks, both interventions were effective in reducing plaque index. The percentage of score reduction was 33% in the experimental group and 30% for the controls, with no significant difference between groups. Both interventions reduced the bleeding index, but this reduction was significant only in the experimental group (P < .001).

Conclusions: There is no difference between chlorhexidine-soaked gauze and CM regarding plaque control. In addition, gauze soaked with chlorhexidine was significantly more effective in reducing the bleeding index score and was appreciated by the patients.

Keywords: chlorhexidine; mouth rinse; oral hygiene; plaque index score; prevention.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Administration, Topical
  • Anti-Infective Agents, Local / administration & dosage
  • Anti-Infective Agents, Local / therapeutic use*
  • Chlorhexidine / administration & dosage
  • Chlorhexidine / therapeutic use*
  • Dental Plaque / drug therapy*
  • Dental Plaque Index
  • Female
  • Humans
  • Italy
  • Male
  • Mouthwashes*
  • Patient Satisfaction
  • Single-Blind Method
  • Toothbrushing
  • Treatment Outcome
  • Young Adult

Substances

  • Anti-Infective Agents, Local
  • Mouthwashes
  • Chlorhexidine