Evaluation of carotid artery elasticity in patients with uremia by echo tracking

J Med Ultrason (2001). 2018 Oct;45(4):591-596. doi: 10.1007/s10396-018-0868-z. Epub 2018 Feb 16.

Abstract

Purpose: The purpose of this study was to compare the carotid artery wall elasticity between patients with uremia and controls using echo tracking (ET).

Methods: Ninety-three patients with uremia and 35 control subjects (Group A) were enrolled in this study. In the ET mode, the carotid artery elasticity parameters including stiffness index (β), pressure-strain elasticity modulus (EP), arterial compliance (AC), and one-point pulse wave velocity (PWVβ) were measured, and carotid intima-media thickness (IMT) was measured with B-mode ultrasonography. The patients were classified into three groups: Group B (normal IMT), Group C (thickened IMT), and Group D (one single atheroma plaque).

Results: β, EP, and PWVβ were significantly higher in Group B, C, and D (especially in group D) than those of the control group (P < 0.05), and there were significant differences between Group A and Group B, while AC was lower than in controls, but there were no statistically significant differences among the four groups.

Conclusions: ET is a noninvasive method that can demonstrate a loss in carotid artery elasticity in uremia patients with normal IMT.

Keywords: Carotid; Echo tracking; Elasticity; Intima–media thickness; Uremia.

MeSH terms

  • Adult
  • Carotid Arteries / diagnostic imaging*
  • Carotid Arteries / physiology
  • Carotid Intima-Media Thickness
  • Elastic Modulus
  • Elasticity Imaging Techniques*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Reproducibility of Results
  • Uremia / diagnostic imaging
  • Uremia / physiopathology
  • User-Computer Interface
  • Young Adult