Vogt-Koyanagi-Harada syndrome Case report

Rom J Ophthalmol. 2016 Jul-Sep;60(3):181-183.

Abstract

Vogt-Koyanagi-Harada syndrome is an uncommon multisystem inflammatory disorder characterized by panuveitis with serous retinal detachment and is often associated with neurologic and cutaneous manifestations including headache, hearing loss, vitiligo, and poliosis. The case of a 62-year-old female with diabetes mellitus and a history of primary open angle glaucoma (POAG) in both eyes, operated on the left eye two weeks prior to the presentation and under topical antiglaucomatous drops, was reported. She presented at the ophthalmological service for decreased visual acuity (VA) in both eyes. The slit lamp examination revealed keratic precipitates and posterior iris synechiae in both eyes and an ExPress aqueous shunt in the left eye. Inferior retinal detachment was observed on ocular fundus examination on both eyes. Intraocular pressure value was in normal range under antiglaucomatous drops (dorzolamid + timolol). The distinctiveness of this case was the association of the VKH syndrome with POAG and the inability to prolong the corticosteroid treatment, necessary in this case, due to the association of diabetes mellitus.

Keywords: Vogt-Koyanagy-Harada; panuveitis; retinal detachment.

Publication types

  • Case Reports

MeSH terms

  • Antihypertensive Agents / therapeutic use
  • Diabetes Complications
  • Female
  • Glaucoma Drainage Implants
  • Glaucoma, Open-Angle / complications*
  • Glaucoma, Open-Angle / diagnosis
  • Glaucoma, Open-Angle / therapy
  • Glucocorticoids / therapeutic use
  • Humans
  • Intraocular Pressure
  • Middle Aged
  • Retinal Detachment / diagnosis
  • Retinal Detachment / etiology
  • Uveomeningoencephalitic Syndrome / complications*
  • Uveomeningoencephalitic Syndrome / diagnosis
  • Uveomeningoencephalitic Syndrome / drug therapy
  • Vision Disorders / diagnosis
  • Vision Disorders / etiology
  • Visual Acuity

Substances

  • Antihypertensive Agents
  • Glucocorticoids