Annotated Genome Sequences of 16 Lineage 4 Mycobacterium tuberculosis Strains from Guatemala

Joseph W Saelens; Dalia Lau-Bonilla; Anneliese Moller; Ana M Xet-Mull; Narda Medina; Brenda Guzmán; Maylena Calderón; Raúl Herrera; Jason E Stout; Eduardo Arathoon; Blanca Samayoa; David M Tobin

doi:10.1128/genomeA.00024-18

Annotated Genome Sequences of 16 Lineage 4 Mycobacterium tuberculosis Strains from Guatemala

Genome Announc. 2018 Feb 15;6(7):e00024-18. doi: 10.1128/genomeA.00024-18.

Authors

Affiliations

¹ Department of Molecular Genetics and Microbiology and Center for Host-Microbial Interactions, Duke University Medical Center, Durham, North Carolina, USA.
² Asociación de Salud Integral, Guatemala City, Guatemala.
³ Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
⁴ Hospital General San Juan de Dios, Guatemala City, Guatemala.
⁵ Clínica Familiar Luis Ángel García, Guatemala City, Guatemala.
⁶ Asociación de Salud Integral, Guatemala City, Guatemala investigacion@asi.org.gt david.tobin@duke.edu.
⁷ Facultad de Ciencias Químicas y Farmacia, Universidad de San Carlos de Guatemala, Guatemala City, Guatemala.
⁸ Department of Molecular Genetics and Microbiology and Center for Host-Microbial Interactions, Duke University Medical Center, Durham, North Carolina, USA investigacion@asi.org.gt david.tobin@duke.edu.

^# Contributed equally.

Abstract

Whole-genome sequencing has resulted in new insights into the phylogeography of Mycobacterium tuberculosis However, only limited genomic data are available from M. tuberculosis strains in Guatemala. Here we report 16 complete genomes of clinical strains belonging to the Euro-American lineage 4, the most common lineage found in Guatemala and Central America.