Successful treatment of non-tuberculous mycobacterial pleurisy with acute fever by antimycobacterial therapy

BMJ Case Rep. 2018 Feb 8:2018:bcr2017222439. doi: 10.1136/bcr-2017-222439.

Abstract

We report two cases of pleurisy caused by non-tuberculous mycobacteria followed by pneumothorax. The onset of pleurisy was accompanied by acute fever. Cultured samples of the pleural effusions from the two patients, an 80-year-old man and an 87-year-old woman, were ultimately found to contain Mycobacterium intracellulare and Mycobacterium kansasii, respectively. Both patients were initially administered antibiotics, but their fevers persisted. Therefore, different combinations of antimycobacterial drugs were used, which reduced the fever in a few days. In these patients, pleurisy caused by non-tuberculous mycobacteria followed by pneumothorax was characterised by acute fever and improvement in the fever after administration of antimycobacterial drugs; however, the aetiology remains to be clarified.

Keywords: infections; pneumonia (respiratory medicine); respiratory system.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use*
  • Antitubercular Agents / therapeutic use*
  • Drug Therapy, Combination
  • Female
  • Fever / etiology
  • Humans
  • Lung / diagnostic imaging
  • Male
  • Mycobacterium Infections, Nontuberculous / diagnosis
  • Mycobacterium Infections, Nontuberculous / drug therapy*
  • Mycobacterium Infections, Nontuberculous / microbiology
  • Mycobacterium avium Complex / isolation & purification
  • Mycobacterium avium-intracellulare Infection / diagnosis
  • Mycobacterium avium-intracellulare Infection / drug therapy*
  • Mycobacterium avium-intracellulare Infection / microbiology
  • Mycobacterium kansasii / isolation & purification
  • Pleurisy / diagnosis
  • Pleurisy / drug therapy*
  • Pleurisy / microbiology
  • Radiography
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Antitubercular Agents