Benefit in liver transplantation: a survey among medical staff, patients, medical students and non-medical university staff and students

BMC Med Ethics. 2018 Feb 12;19(1):7. doi: 10.1186/s12910-018-0248-7.

Abstract

Background: The allocation of any scarce health care resource, especially a lifesaving resource, can create profound ethical and legal challenges. Liver transplant allocation currently is based upon urgency, a sickest-first approach, and does not utilize capacity to benefit. While urgency can be described reasonably well with the MELD system, benefit encompasses multiple dimensions of patients' well-being. Currently, the balance between both principles is ill-defined.

Methods: This survey with 502 participants examines how urgency and benefit are weighted by different stakeholders (medical staff, patients on the liver transplant list or already transplanted, medical students and non-medical university staff and students).

Results: Liver transplant patients favored the sickest-first allocation, although all other groups tended to favor benefit. Criteria of a successful transplantation were a minimum survival of at least 1 year and recovery of functional status to being ambulatory and capable of all self-care (ECOG 2). An individual delisting decision was accepted when the 1-year survival probability would fall below 50%. Benefit was found to be a critical variable that may also trigger the willingness to donate organs.

Conclusions: The strong interest of stakeholder for successful liver transplants is inadequately translated into current allocation rules.

Keywords: Allocation; Benefit; Ethics; Legal aspects; Liver transplantation; Prospect of success; Quality of life; Urgency; Utility; Willingness to donate.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Attitude*
  • Beneficence
  • Female
  • Humans
  • Liver Transplantation / ethics*
  • Male
  • Medical Staff
  • Middle Aged
  • Patient Selection*
  • Principle-Based Ethics*
  • Stakeholder Participation
  • Students, Medical
  • Surveys and Questionnaires
  • Tissue and Organ Procurement*
  • Universities
  • Waiting Lists*
  • Young Adult