Total Renal Artery Occlusion: Recovery of Function After Revascularization

Am J Kidney Dis. 2018 May;71(5):748-753. doi: 10.1053/j.ajkd.2017.11.014. Epub 2018 Feb 9.

Abstract

Current trends in managing atherosclerotic renal artery stenosis favor medical therapy, on account of negative results from prospective trials of revascularization, such as CORAL and ASTRAL. One result of this trend has been encountering occasional patients with progressive disease, sometimes leading to total arterial occlusion. We illustrate a case of accelerated hypertension with complete renal artery occlusion in which the patient recovered function after surgical bypass and we review the clinical approach used and the advanced imaging modalities available to us. A high index of suspicion and careful radiologic imaging play important roles in selecting patients who may have residual function and may benefit from revascularization. This case illustrates an example whereby restoring renal artery perfusion for carefully selected patients can be life changing, with recovery of kidney function and improved blood pressure, pill burden, and overall quality of life.

Keywords: Atherosclerotic renovascular disease (ARVD); blood oxygen level-dependent magnetic resonance (BOLD-MR); case report; hypertension; imaging; renal artery stenosis; renal ischemic disease; revascularization; total renal artery occlusion.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Computed Tomography Angiography / methods*
  • Female
  • Follow-Up Studies
  • Humans
  • Hypertension, Renovascular / complications*
  • Hypertension, Renovascular / diagnostic imaging
  • Hypertension, Renovascular / physiopathology
  • Imaging, Three-Dimensional*
  • Kidney Function Tests
  • Prognosis
  • Recovery of Function
  • Renal Artery Obstruction / diagnostic imaging
  • Renal Artery Obstruction / etiology
  • Renal Artery Obstruction / surgery*
  • Risk Assessment
  • Severity of Illness Index
  • Treatment Outcome
  • Vascular Patency
  • Vascular Surgical Procedures / methods*