Germline gain-of-function myeloid differentiation primary response gene-88 (MYD88) mutation in a child with severe arthritis

J Allergy Clin Immunol. 2018 May;141(5):1943-1947.e9. doi: 10.1016/j.jaci.2018.01.027. Epub 2018 Feb 7.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, N.I.H., Intramural

MeSH terms

  • Adaptor Proteins, Signal Transducing / genetics
  • Adolescent
  • Arthritis / genetics*
  • Bone and Bones / pathology
  • C-Reactive Protein / genetics
  • Cell Differentiation / genetics*
  • Cell Line
  • Exome / genetics
  • Female
  • Gain of Function Mutation / genetics*
  • Germ Cells / pathology*
  • Humans
  • Inflammation / genetics
  • Monocytes / pathology
  • Mutation / genetics*
  • Myeloid Differentiation Factor 88 / genetics*

Substances

  • Adaptor Proteins, Signal Transducing
  • MYD88 protein, human
  • Myeloid Differentiation Factor 88
  • C-Reactive Protein