Acute kidney injury in major abdominal surgery: incidence, risk factors, pathogenesis and outcomes

Joana Gameiro; José Agapito Fonseca; Marta Neves; Sofia Jorge; José António Lopes

doi:10.1186/s13613-018-0369-7

Acute kidney injury in major abdominal surgery: incidence, risk factors, pathogenesis and outcomes

Ann Intensive Care. 2018 Feb 9;8(1):22. doi: 10.1186/s13613-018-0369-7.

Authors

Joana Gameiro¹, José Agapito Fonseca², Marta Neves², Sofia Jorge², José António Lopes²

Affiliations

¹ Division of Nephrology and Renal Transplantation, Department of Medicine, Centro Hospitalar Lisboa Norte, EPE, Av. Prof. Egas Moniz, 1649-035, Lisbon, Portugal. joana.estrelagameiro@gmail.com.
² Division of Nephrology and Renal Transplantation, Department of Medicine, Centro Hospitalar Lisboa Norte, EPE, Av. Prof. Egas Moniz, 1649-035, Lisbon, Portugal.

Abstract

Acute kidney injury (AKI) is a common complication in patients undergoing major abdominal surgery. Various recent studies using modern standardized classifications for AKI reported a variable incidence of AKI after major abdominal surgery ranging from 3 to 35%. Several patient-related, procedure-related factors and postoperative complications were identified as risk factors for AKI in this setting. AKI following major abdominal surgery has been shown to be associated with poor short- and long-term outcomes. Herein, we provide a contemporary and critical review of AKI after major abdominal surgery focusing on its incidence, risk factors, pathogeny and outcomes.

Keywords: Acute kidney injury; Incidence; Pathogenesis; Postoperative; Prognosis; Risk factors.

Publication types

Review