Treatment of tibial nonunion with bone defect using a heterotopic ossification as autologous bone graft: literature overview and case report

Eur J Orthop Surg Traumatol. 2018 May;28(4):741-746. doi: 10.1007/s00590-018-2146-6. Epub 2018 Feb 9.

Abstract

Introduction: Nonunion after open fracture of the lower leg is a frequent complication with a prevalence of up to 40%. In cases with major bone defects, revision of the osteosynthesis with bone grafting is commonly performed. Until today, there is no report on treatment of a tibial nonunion with transplantation of a heterotopic ossification.

Presentation of case: We present a case of a 27-year-old male patient, who suffered from a paragliding accident with major injuries. An open fracture of the lower leg (Gustilo-Anderson IIIB) was initially treated with external fixation and vacuum-assisted closure, followed by reamed intramedullary nailing. The tibia resulted in a bone defect situation with nonunion. It was successfully treated with revision, fibular osteotomy and transplantation of a heterotopic ossification, harvested from the ipsilateral hip.

Conclusion: In special cases, autologous transplantation of a mature heterotopic ossification is an attractive bone graft option in treating nonunion defects.

Keywords: Bone defect; Bone graft; Heterotopic ossification; Nonunion; Open fracture; Tibia.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Accidents, Aviation
  • Adult
  • Bone Transplantation / methods*
  • Fracture Fixation, Internal / methods*
  • Fractures, Ununited / surgery*
  • Humans
  • Male
  • Ossification, Heterotopic / etiology*
  • Reoperation
  • Tibial Fractures / surgery*
  • Transplantation, Autologous / methods