Relationship Between Postpartum Depression and Psychological and Biological Variables in the Initial Postpartum Period

Matern Child Health J. 2018 Jun;22(6):866-873. doi: 10.1007/s10995-018-2461-x.

Abstract

Objectives The aims of this study were to evaluate the predictive relationship between psychological symptomatology 24 h postpartum and depression 4 months postpartum, and analyze the relationship between estradiol and postpartum mood. Methods Two hundred women participated in an assessment 24 h postpartum and gave a blood sample for estradiol analysis. One hundred eleven of these women completed the second assessment 4 months postpartum. The Beck Depression Inventory II and the Scale of State-Trait Anxiety were used to assess psychological symptoms. Results At 24 h postpartum, symptoms of depression, trait anxiety, and state anxiety were all significantly correlated with each other. Depression at 24 h postpartum was the only significant independent predictor of depression at 4 months postpartum, explaining 28.7% of the variance. No statistically significant relationship was found between levels of estradiol and mood. Symptoms of depression immediately postpartum thus appear to be a predictor of postpartum depression. Conclusions for Practice These results suggest that early postpartum psychological evaluation of the mother, and intervention as warranted, might prevent or lessen postpartum depression.

Keywords: Anxiety; Childbirth; Estradiol; Postpartum depression.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anxiety / blood
  • Anxiety / diagnosis*
  • Anxiety / epidemiology
  • Depression, Postpartum / blood
  • Depression, Postpartum / diagnosis*
  • Depression, Postpartum / epidemiology
  • Estradiol / blood*
  • Female
  • Follow-Up Studies
  • Humans
  • Mothers / psychology*
  • Postpartum Period / psychology*
  • Pregnancy
  • Psychiatric Status Rating Scales / statistics & numerical data*
  • Spain / epidemiology
  • Surveys and Questionnaires
  • Young Adult

Substances

  • Estradiol