Nutritional Aspects of Acute Pancreatitis

Gastroenterol Clin North Am. 2018 Mar;47(1):77-94. doi: 10.1016/j.gtc.2017.10.002. Epub 2017 Dec 6.

Abstract

The goal of nutritional support in acute pancreatitis is to reduce inflammation, prevent nutritional depletion, correct a negative nitrogen balance, and improve outcomes. Enteral nutrition (EN) in severe acute pancreatitis (SAP) should be preferred to parenteral nutrition. It maintains the integrity of the gut barrier, decreases intestinal permeability, downregulates the systemic inflammatory response, maintains intestinal microbiota equilibrium, and reduces the complications of the early phase of SAP, improving morbidity and possibly improving mortality, and it is less expensive. Further studies to understand optimal timing of nutrition, route of delivery of EN, and the type of nutrition and nutrients are necessary.

Keywords: Acute pancreatitis; Enteral; Nutrition; Parenteral.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Eating
  • Enteral Nutrition*
  • Humans
  • Intestinal Absorption
  • Malnutrition / etiology
  • Nutrition Assessment*
  • Pancreatitis / complications
  • Pancreatitis / physiopathology*
  • Pancreatitis / therapy*
  • Severity of Illness Index