Abscisic acid: new perspectives on an ancient universal stress signaling molecule

Microbes Infect. 2018 Oct-Nov;20(9-10):484-492. doi: 10.1016/j.micinf.2018.01.009. Epub 2018 Feb 1.

Abstract

Few biological molecules have as far reaching and dynamic effects as abscisic acid (ABA). In this review, we draw together the often segregated fields of plant, animal, and human biology to highlight ABA biosynthesis, signaling and physiological effects with examples of host-pathogen interactions to emphasize the cross-kingdom biology of this ancient signaling molecule.

Keywords: Abscisic acid; Host–microbe interactions; Immune regulation; Mevalonate pathway; Non-mevalonate pathway; Stress response.

Publication types

  • Review

MeSH terms

  • Abscisic Acid / biosynthesis
  • Abscisic Acid / chemistry
  • Abscisic Acid / pharmacology
  • Abscisic Acid / physiology*
  • Animals
  • Host-Pathogen Interactions
  • Humans
  • Immunity / drug effects
  • Plant Physiological Phenomena / drug effects
  • Signal Transduction*
  • Stress, Physiological*

Substances

  • Abscisic Acid