One-Stage Complete Resection of Cholesteatoma With Labyrinthine Fistula: Hearing Changes and Clinical Outcomes

Ann Otol Rhinol Laryngol. 2018 Apr;127(4):241-248. doi: 10.1177/0003489418755407. Epub 2018 Feb 6.

Abstract

Objectives: To evaluate long-term hearing changes and surgical outcomes for middle ear cholesteatoma with labyrinthine fistula following complete surgical removal of the cholesteatoma matrix.

Methods: Consecutive samples of 43 patients who underwent 1-stage complete resection of the cholesteatoma matrix overlying a labyrinthine fistula were obtained. Immediate and long-term hearing changes were analyzed in association with fistula size. Accuracy of various diagnostic examinations was assessed.

Results: Immediately postsurgery, the average bone conduction threshold (43.34 dB) did not differ significantly from the preoperative value (36.66 dB, P = .083). There were also minimal changes thereafter (45.63 dB) without recurrent case over an average follow-up time of 38.3 months (range, 17-69 months). More than 10 dB hearing loss was found in 7 patients with a case of intraoperative perilymph leakage (2.3%), although 5 of them had had preoperative air conduction threshold above 90 dB. Their fistulas were significantly larger than those of patients without hearing loss ( P = .027).

Conclusion: Although caution is required for total removal of a large fistula, owing to increased risk of postoperative hearing deterioration, 1-stage complete resection of cholesteatoma matrix on labyrinthine fistula could be effective in disease control and long-term hearing preservation.

Keywords: cholesteatoma; hearing loss; labyrinthine fistula; recurrence; surgical resection.

MeSH terms

  • Adult
  • Aged
  • Cholesteatoma, Middle Ear* / pathology
  • Cholesteatoma, Middle Ear* / physiopathology
  • Cholesteatoma, Middle Ear* / surgery
  • Diagnostic Techniques, Otological
  • Dimensional Measurement Accuracy
  • Dissection / methods
  • Ear, Inner* / diagnostic imaging
  • Ear, Inner* / pathology
  • Female
  • Fistula* / diagnostic imaging
  • Fistula* / surgery
  • Hearing Loss* / diagnosis
  • Hearing Loss* / etiology
  • Humans
  • Labyrinth Diseases* / diagnosis
  • Labyrinth Diseases* / physiopathology
  • Labyrinth Diseases* / surgery
  • Male
  • Middle Aged
  • Otologic Surgical Procedures* / adverse effects
  • Otologic Surgical Procedures* / methods
  • Outcome Assessment, Health Care
  • Postoperative Complications / diagnosis*
  • Republic of Korea
  • Retrospective Studies