Epidermoid cyst is a benign and rare tumor, that evolves slowly. We describe the case of a 55 years-old woman, who came to our consultation for atypical trigeminal neuralgia of left V1 and V2 nerves. Brain MRI found two tumors: T1W hypointense with no appreciable enhancement after gadolinium injection and T2W and diffusion hyperintense. This last feature was in favour of an epidermoid cyst, but the multiplicity of cerebral lesions was definitely not in favor of such a diagnostic. They were located behind the right eye and in the left Meckel’s cave (trigeminal cave). The surgical strategy consisted in removal the retro orbital tumor witch was the most accessible of both the diagnostic of epidermoid cyst was retaned thanks to the anatomopathology report. As these lesions had the exact same characteristics, we concluded that they were similar. The second epidermoid cyst was not removed because of surgical risk, its benign nature and low evolutionary potential.