The choice between deceased- vs living-donor renal transplantation in children: Analysis of data from a Belgian tertiary center

Pediatr Transplant. 2018 Mar;22(2). doi: 10.1111/petr.13140. Epub 2018 Feb 4.

Abstract

Pediatric renal transplantation with a living donor (LD) has superior outcome, but there is a paucity of studies analyzing the reasons for not undertaking living donation in West-European countries. The aim of this study was to retrospectively review the choice of donor source in our center. We also aimed to identify factors which prevented transplantation with a LD. This retrospective study was performed including children aged 2-19 years who underwent kidney transplantation (KT) at the Ghent University Hospital between 1996 and 2016. Relevant data were collected from medical files to identify the main medical, psychological, and socio-economic factors influencing the choice of the donor source. There were 48 patients (boys n = 33) who underwent KT. Thirty-nine patients received a deceased donor (DD) kidney and nine patients received a LD kidney. Sixteen of 48 transplantations were preemptive. The reasons for DD KT included socio-economic factors such as single caregiver families, one or both parents with a criminal record or convictions and religious or cultural constraints (n = 15), medical considerations (n = 13), refusal of the close relatives/parents to donate (n = 7), and acceptance of an organ from a DD while prospective donor was undergoing medical screening (n = 4). The low incidence of living kidney donation can be explained by socio-economic and medical factors. Refusal to donate is a potentially modifiable factor and strategies aimed at education and guidance of the families might contribute to a higher incidence of living donation in our setting.

Keywords: kidney transplantation; organ donation; pediatric; socio-economic factors; transplantation.

MeSH terms

  • Adolescent
  • Belgium
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Kidney Transplantation*
  • Living Donors / statistics & numerical data
  • Living Donors / supply & distribution*
  • Male
  • Retrospective Studies
  • Socioeconomic Factors
  • Tissue and Organ Procurement / methods*
  • Tissue and Organ Procurement / statistics & numerical data
  • Tissue and Organ Procurement / trends
  • Young Adult