Therapeutic Opportunities in Intestinal Microbiota-Virus Interactions

Trends Biotechnol. 2018 Jul;36(7):645-648. doi: 10.1016/j.tibtech.2017.12.009. Epub 2018 Jan 24.

Abstract

The host microbiota has emerged a third player in interactions between hosts and viral pathogens. This opens new possibilities to use different tools to modulate the intestinal microbial composition, aimed at reducing the risk of or treating viral enteric infections.

Keywords: histo-blood group antigens; intestinal microbiota; norovirus; probiotics; rotavirus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Animals
  • Caliciviridae Infections / microbiology*
  • Caliciviridae Infections / therapy
  • Child, Preschool
  • Gastrointestinal Microbiome* / drug effects
  • Gastrointestinal Microbiome* / immunology
  • Gastrointestinal Tract / immunology
  • Gastrointestinal Tract / microbiology
  • Gastrointestinal Tract / virology
  • Host-Pathogen Interactions / immunology
  • Humans
  • Immune System / immunology
  • Norovirus / drug effects*
  • Norovirus / pathogenicity
  • Norovirus / physiology
  • Probiotics / pharmacology*
  • Probiotics / therapeutic use
  • Rotavirus / drug effects*
  • Rotavirus / pathogenicity
  • Rotavirus / physiology
  • Rotavirus Infections / microbiology*
  • Rotavirus Infections / therapy
  • Specific Pathogen-Free Organisms