Recent developments in dopamine-based materials for cancer diagnosis and therapy

Adv Colloid Interface Sci. 2018 Feb:252:1-20. doi: 10.1016/j.cis.2018.01.001. Epub 2018 Jan 31.

Abstract

Dopamine-based materials are emerging as novel biomaterials and have attracted considerable interests in the fields of biosensing, bioimaging and cancer therapy due to their unique physicochemical properties, such as versatile adhesion property, high chemical reactivity, excellent biocompatibility and biodegradability, strong photothermal conversion capacity, etc. In this review, we present an overview of recent research progress on dopamine-based materials for diagnosis and therapy of cancer. The review starts with a summary of the physicochemical properties of dopamine-based materials in general. Then detailed description is followed on their applications in the fields of diagnosis and treatment of cancers. The review concludes with an outline of some remaining challenges for dopamine-based materials to be used for clinical applications.

Keywords: Bioimaging; Biosensing; Cancer therapy; Nanomaterials; Polydopamine.

Publication types

  • Review

MeSH terms

  • Animals
  • Dopamine / chemistry*
  • Dopamine / therapeutic use*
  • Humans
  • Neoplasms / diagnosis*
  • Neoplasms / therapy*

Substances

  • Dopamine