Diagnostic Electron Microscopy of Retina

Semin Ophthalmol. 2018;33(5):700-710. doi: 10.1080/08820538.2017.1416415. Epub 2018 Feb 1.

Abstract

The electron microscopy techniques were used in various fields as an analytical technique under in vitro conditions, which provides the sufficient resolution for better visualization and interpretation. This review gives a brief overview of the analytical application of transmission electron microscopy (TEM) and scanning electron microscopy (SEM) techniques and critical findings in different retinal pathologies. This review article aims to improvise understanding of retinal microstructures for clinicians which will help to improve the interpretation of the current advanced imaging techniques.

Keywords: Age-related macular degeneration (AMD); Photoreceptors; Retinal degeneration; Transmission electron microscopy (TEM); Ultrastructure.

Publication types

  • Review

MeSH terms

  • Humans
  • Microscopy, Electron, Scanning / methods*
  • Reproducibility of Results
  • Retina / ultrastructure*
  • Retinal Degeneration / diagnosis*