Intravitreal bevacizumab associated with photodynamic therapy in a case of polypoidal choroidal vasculopathy associated with choroidal nevus: A case report

Medicine (Baltimore). 2017 Dec;96(52):e9400. doi: 10.1097/MD.0000000000009400.

Abstract

Rationale: Report the clinical findings and management of a case of polypoidal choroidal vasculopathy associated with choroidal nevus which received combination therapy.

Patient concerns: Decreased visual acuity in a woman with polypoidal choroidal vasculopathy and choroidal nevus.

Diagnoses: Polypoidal choroidal vasculopathy and choroidal nevus.

Interventions: The initial visual acuity was 0.5. After the first treatment with photodynamic therapy, exudation and bleeding appeared around the lesion. After this, the patient received 3 doses of intravitreal bevacizumab.

Outcomes: After treatment with combination therapy, visual acuity, clinical and imaging findings improved, with no recurrence of exudation and bleeding.

Lessons: Intravitreal bevacizumab as an adjunctive treatment after photodynamic therapy is a good option for patients with polypoidal choroidal vasculopathy associated with choroidal nevus.

Publication types

  • Case Reports

MeSH terms

  • Angiogenesis Inhibitors / therapeutic use*
  • Bevacizumab / therapeutic use*
  • Choroid Neoplasms / complications
  • Choroid Neoplasms / diagnostic imaging
  • Choroid Neoplasms / drug therapy*
  • Choroidal Neovascularization / complications
  • Choroidal Neovascularization / diagnostic imaging
  • Choroidal Neovascularization / drug therapy*
  • Female
  • Humans
  • Middle Aged
  • Nevus / complications
  • Nevus / diagnostic imaging
  • Nevus / drug therapy*
  • Photochemotherapy*

Substances

  • Angiogenesis Inhibitors
  • Bevacizumab