Recommendations for the use of molecular diagnostics in the diagnosis of allergic diseases

Eur Ann Allergy Clin Immunol. 2018 Mar;50(2):51-58. doi: 10.23822/EurAnnACI.1764-1489.32. Epub 2017 Nov 27.

Abstract

The Study Group on Allergology of the Italian Society of Clinical Pathology and Laboratory Medicine (SIPMeL) and the Associazione Italiana degli Allergologi e Immunologi Territoriali e Ospedalieri (AAIITO) developed the present recommendations on the diagnosis of allergic diseases based on the use of molecular allergenic components, whose purpose is to provide the pathologists and the clinicians with information and algorithms enabling a proper use of this second-level diagnostics. Molecular diagnostics allows definition of the exact sensitization profile of the allergic patient. The methodology followed to develop these recommendations included an initial phase of discussion between all the components to integrate the knowledge derived from scientific evidence, a revision of the recommendations made by Italian and foreign experts, and the subsequent production of this document to be disseminated to all those who deal with allergy diagnostics.

Keywords: allergy; component resolved diagnostics; guidelines; molecular diagnostics; specific IgE.

Publication types

  • Review

MeSH terms

  • Algorithms
  • Allergens / immunology*
  • Allergens / isolation & purification
  • Humans
  • Hypersensitivity / diagnosis*
  • Immunoglobulin E / immunology*
  • Pathology, Molecular / methods*

Substances

  • Allergens
  • Immunoglobulin E