Dearylation of arylphosphine oxides using a sodium hydride-iodide composite

Ciputra Tejo; Jia Hao Pang; Derek Yiren Ong; Miku Oi; Masanobu Uchiyama; Ryo Takita; Shunsuke Chiba

doi:10.1039/c8cc00289d

Dearylation of arylphosphine oxides using a sodium hydride-iodide composite

Chem Commun (Camb). 2018 Feb 13;54(14):1782-1785. doi: 10.1039/c8cc00289d.

Authors

Ciputra Tejo¹, Jia Hao Pang, Derek Yiren Ong, Miku Oi, Masanobu Uchiyama, Ryo Takita, Shunsuke Chiba

Affiliation

¹ Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore. shunsuke@ntu.edu.sg.

PMID: 29383363
DOI: 10.1039/c8cc00289d

Abstract

A new protocol for the dearylation of arylphosphine oxides was developed using sodium hydride (NaH) in the presence of lithium iodide (LiI). The transient sodium phosphinite could be functionalized with a range of electrophiles in a one-pot fashion.