CD8+CD28- T cells: not only age-related cells but a subset of regulatory T cells

Cell Mol Immunol. 2018 Aug;15(8):734-736. doi: 10.1038/cmi.2017.153. Epub 2018 Jan 29.

Authors

Xiaoyong Chen¹, Qiuli Liu², Andy Peng Xiang³

Affiliations

¹ Center for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-Sen University, Guangzhou, China.
² The Biotherapy Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
³ Center for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-Sen University, Guangzhou, China. xiangp@mail.sysu.edu.cn.

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aged
Aged, 80 and over
Animals
Antigen-Presenting Cells / immunology
Antigen-Presenting Cells / metabolism
Apoptosis
Autoimmune Diseases / immunology
Biomarkers
CD28 Antigens / physiology*
CD8-Positive T-Lymphocytes / immunology*
CD8-Positive T-Lymphocytes / metabolism
Cell- and Tissue-Based Therapy
Cellular Senescence / immunology*
Coculture Techniques
Graft vs Host Disease / therapy
Humans
Immunomodulation
Infant, Newborn
Inflammation / therapy
Mesenchymal Stem Cell Transplantation
Mesenchymal Stem Cells / metabolism
Mice
T-Lymphocytes, Regulatory / immunology*
T-Lymphocytes, Regulatory / metabolism
Tumor Microenvironment / immunology

Substances

Biomarkers
CD28 Antigens
TMIGD2 protein, human