[Advances in the research of relationship between CD26 and hypertrophic scar and keloid]

C L Song; M Yao

doi:10.3760/cma.j.issn.1009-2587.2018.01.011

[Advances in the research of relationship between CD26 and hypertrophic scar and keloid]

Zhonghua Shao Shang Za Zhi. 2018 Jan 20;34(1):54-56. doi: 10.3760/cma.j.issn.1009-2587.2018.01.011.

[Article in Chinese]

Authors

C L Song¹, M Yao

Affiliation

¹ Department of Plastic Surgery and Burns, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201900, China.

PMID: 29374928
DOI: 10.3760/cma.j.issn.1009-2587.2018.01.011

Abstract

In recent years, researchers have found that CD26 (dipeptidyl peptidase 4) is closely related to the formation and development of many fibrotic diseases. Hypertrophic scar, keloid, and other skin fibrosis diseases are major problems nowadays, which may affect the patient's appearance and cause joints deformity and dysfunction due to scar contracture. This article briefly reviews the relationship between CD26 and hypertrophic scar and keloid to provide new insights into the treatment of skin fibrotic diseases.

Keywords: CD26; Dipeptidyl peptidase 4; Fibrosis; Hypertrophic scar; Keloid.

Publication types

Review

MeSH terms

Cicatrix, Hypertrophic / pathology*
Dipeptidyl Peptidase 4 / metabolism*
Fibrosis
Humans
Keloid / pathology*

Substances

DPP4 protein, human
Dipeptidyl Peptidase 4