Second-Generation Antipsychotic-Induced Hypoglycemia

Tomonari Fujita; Yoshito Mizoguchi; Yutaka Kunitake; Hiroshi Tateishi; Takayoshi Inaba; Takahiro A Kato; Akira Monji

doi:10.4088/PCC.17br02186

Second-Generation Antipsychotic-Induced Hypoglycemia

Prim Care Companion CNS Disord. 2018 Jan 25;20(1):17br02186. doi: 10.4088/PCC.17br02186.

Authors

Tomonari Fujita¹, Yoshito Mizoguchi¹, Yutaka Kunitake¹, Hiroshi Tateishi¹, Takayoshi Inaba¹, Takahiro A Kato², Akira Monji^{1

3}

Affiliations

¹ Department of Psychiatry, Faculty of Medicine, Saga University, Saga City, Japan.
² Department of Neuropsychiatry, Faculty of Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka City, Japan.
³ Department of Psychiatry, Faculty of Medicine, Saga University, Nabeshima5-1-1, Saga-city 849-8501, Japan.amonji@hf.rim.or.jp.

PMID: 29372938
DOI: 10.4088/PCC.17br02186

Abstract

Complaints of hypoglycemia resemble the sedative effect of antipsychotics. As such, clinicians may overlook hypoglycemia in patients with psychiatric disorders. Here, a case of hypoglycemia associated with hyperinsulinemia induced by quetiapine in a female patient with bipolar disorder is reported. The case suggests that clinicians should be aware of the potential for hypoglycemia induced by second-generation antipsychotics.

MeSH terms

Antidepressive Agents / adverse effects
Antidepressive Agents / therapeutic use
Antipsychotic Agents / adverse effects*
Antipsychotic Agents / therapeutic use
Bipolar Disorder / blood
Bipolar Disorder / complications
Bipolar Disorder / diagnosis
Bipolar Disorder / drug therapy
Depressive Disorder, Major / blood
Depressive Disorder, Major / complications
Depressive Disorder, Major / diagnosis
Depressive Disorder, Major / drug therapy
Diagnostic Errors
Female
Humans
Hypoglycemia / blood
Hypoglycemia / diagnosis
Hypoglycemia / etiology*
Middle Aged
Quetiapine Fumarate / adverse effects
Quetiapine Fumarate / therapeutic use

Substances

Antidepressive Agents
Antipsychotic Agents
Quetiapine Fumarate