Advanced endoscopic imaging for diagnosis of inflammatory bowel diseases: Present and future perspectives

Dig Endosc. 2018 Jul;30(4):441-448. doi: 10.1111/den.13023. Epub 2018 Feb 19.

Abstract

Crohn's disease and ulcerative colitis are chronic inflammatory bowel diseases (IBD) causing severe damage of the luminal gastrointestinal tract. Differential diagnosis between both disease entities is sometimes awkward requiring a multifactorial pathway, including clinical and laboratory data, radiological findings, histopathology and endoscopy. Apart from disease diagnosis, endoscopy in IBD plays a major role in prediction of disease severity and extent (i.e. mucosal healing) for tailored patient management and for screening of colitis-associated cancer and its precursor lesions. In this state-of-the-art review, we focus on current applications of endoscopy for diagnosis and surveillance of IBD. Moreover, we will discuss the latest guidelines on surveillance and provide an overview of the most recent developments in the field of endoscopic imaging and IBD.

Keywords: BLI; IBD; LCI; NBI; advanced imaging.

Publication types

  • Review

MeSH terms

  • Chromogenic Compounds / pharmacology
  • Colitis, Ulcerative / diagnosis*
  • Colitis, Ulcerative / pathology
  • Crohn Disease / diagnosis*
  • Crohn Disease / pathology
  • Cross-Over Studies
  • Diagnosis, Differential
  • Endoscopy, Gastrointestinal / methods*
  • Endoscopy, Gastrointestinal / trends*
  • Female
  • Forecasting
  • Humans
  • Image Enhancement / methods
  • Inflammatory Bowel Diseases / diagnosis
  • Inflammatory Bowel Diseases / pathology
  • Intestinal Mucosa / pathology*
  • Male
  • Microscopy, Confocal / methods
  • Molecular Imaging / methods
  • Molecular Imaging / trends
  • Precision Medicine / methods
  • Precision Medicine / trends
  • Prospective Studies
  • Randomized Controlled Trials as Topic

Substances

  • Chromogenic Compounds