Hidradenitis suppurativa, a review of pathogenesis, associations and management. Part 1

Dunja Ana Vekic; John Frew; Geoffrey David Cains

doi:10.1111/ajd.12770

Hidradenitis suppurativa, a review of pathogenesis, associations and management. Part 1

Australas J Dermatol. 2018 Nov;59(4):267-277. doi: 10.1111/ajd.12770. Epub 2018 Jan 21.

Authors

Dunja Ana Vekic^{1

2

3}, John Frew^{2

3}, Geoffrey David Cains^{1

3}

Affiliations

¹ Ingham Institute for Applied Medical Research, Sydney, New South Wales, Australia.
² Department of Dermatology, Liverpool Hospital, Sydney, New South Wales, Australia.
³ University of New South Wales, Sydney, New South Wales, Australia.

PMID: 29355905
DOI: 10.1111/ajd.12770

Abstract

Hidradenitis suppurativa is a chronic, painful, autoinflammatory condition resulting in nodules, abscesses and sinus tracts. We present an evidence-based review providing new understanding of the pathogenesis of hidradenitis suppurativa and associated comorbidities. By the nature of their speciality, dermatologists are uniquely positioned to investigate and treat patients with this condition. Data collected from a subspecialty hidradenitis suppurativa clinic (N = 106) and experiences thereof are discussed in this review.

Keywords: autoinflammation; hidradenitis suppurativa.

Publication types

Review

MeSH terms

Biofilms
Comorbidity*
Diagnosis, Differential
Hidradenitis Suppurativa / diagnosis*
Hidradenitis Suppurativa / epidemiology
Hidradenitis Suppurativa / etiology*
Humans
Inflammasomes*
Microbiota
Phenotype
Severity of Illness Index

Substances

Inflammasomes