An unusual case of positive sIgE to Galactose-alpha-1,3-galactose from South Italy

Eur Ann Allergy Clin Immunol. 2018 Jan;50(1):45-47. doi: 10.23822/EurAnnACI.1764-1489.25.

Abstract

We report the case of a 38-year-old man who was bitten several times during his life by a tick. He didn't report any previous history of anaphylaxis after the ingestion of red meat. The serum specific IgE showed positivity to α-Gal. The proximity of the bits didn't increase the titer of IgE antibodies to alpha-gal. We could hypothesize that the frequency of the exposure to the tick Corresponding author bites and the amount of tick bites during his lifetime induced a sort of tolerance in this patient.

Keywords: basophil activation test; delayed food anaphylaxis; hunter; sIgE to α-Gal; tick bit.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Allergens / immunology*
  • Anaphylaxis / diagnosis*
  • Animals
  • Basophil Degranulation Test
  • Food Hypersensitivity / diagnosis*
  • Humans
  • Hypersensitivity, Delayed
  • Immunoglobulin E / metabolism
  • Italy
  • Ixodes / immunology
  • Male
  • Meat Proteins / immunology
  • Red Meat
  • Tick Bites / diagnosis*
  • Tick-Borne Diseases / diagnosis*
  • alpha-Galactosidase / immunology*

Substances

  • Allergens
  • Meat Proteins
  • Immunoglobulin E
  • GLA protein, human
  • alpha-Galactosidase