Brain metastases epidemiology in a Tunisian population: trends and outcome

CNS Oncol. 2018 Jan;7(1):35-39. doi: 10.2217/cns-2017-0020. Epub 2018 Jan 19.

Abstract

Aim: We reported anatomo-clinical features of brain metastases (BMs) collected in a Tunisian medical oncology department.

Patients & methods: We retrospectively identified all cases of BM within a cohort of 7055 patients, treated for a histologically confirmed nonhematological cancer between 2000 and 2016. Data about age, sex and primary tumor were collected.

Results: Incidence was 1.9% and mean age was 54 years with a 1.24 sex ratio. BMs were symptomatic in 73.7% of cases after a median time of 16 months. A total of 73.4% patients receiving local therapy, 88% by whole brain radiation therapy and 21.6% had a metastasectomy. Lung and breast cancers were the primary in 80% of the BM.

Conclusion: BM showed trends of young with underestimated incidence.

Keywords: brain metastases; epidemiology; survival.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Brain Neoplasms / epidemiology*
  • Brain Neoplasms / secondary*
  • Brain Neoplasms / therapy
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Retrospective Studies
  • Survival Analysis
  • Tunisia / epidemiology