Author Response: Penetrance of the LHON Mutation m.11778G>A May Depend on Factors Other Than Haplotype or Heteroplasmy Rate
Invest Ophthalmol Vis Sci
.
2018 Jan 1;59(1):382.
doi: 10.1167/iovs.17-23468.
Authors
Nahid Akhtar Khan
1
,
Periyasamy Govindaraj
2
3
,
Nagasamy Soumittra
4
,
Sonika Sharma
1
,
Sundaramoorthy Srilekha
4
,
Selvakumar Ambika
5
,
Ayyasamy Vanniarajan
1
6
,
Angamuthu Kanikannan Meena
7
,
Megha S Uppin
8
,
Challa Sundaram
8
,
Parayil Sankaran Bindu
3
9
,
Narayanappa Gayathri
2
3
,
Arun B Taly
3
9
,
Kumarasamy Thangaraj
1
Affiliations
1
CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
2
Department of Neuropathology, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, India.
3
Neuromuscular Laboratory, Neurobiology Research Centre, NIMHANS, Bengaluru, India.
4
SNONGC Department of Genetics and Molecular Biology, Vision Research Foundation, Sankara Nethralaya, Chennai, India.
5
Department of Neuro-Ophthalmology, Medical Research Foundation, Sankara Nethralaya Chennai, India.
6
Department of Molecular Genetics, Aravind Medical Research Foundation, Madurai, India.
7
Department of Neurology, Nizam's Institute Medical Sciences (NIMS), Hyderabad, India.
8
Department of Pathology, Nizam's Institute Medical Sciences (NIMS), Hyderabad, India; and the.
9
Department of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, India.
PMID:
29346803
DOI:
10.1167/iovs.17-23468
No abstract available
Publication types
Letter
Research Support, Non-U.S. Gov't
Comment
MeSH terms
DNA, Mitochondrial
Haplotypes*
Humans
Mutation
Optic Atrophy, Hereditary, Leber
Pedigree
Penetrance*
Substances
DNA, Mitochondrial