Recent Progress in Chemosensors Using Aldehyde-bearing Fluorophores for the Detection of Specific Analytes and their Bioimaging

Curr Med Chem. 2019;26(21):4003-4028. doi: 10.2174/0929867325666180117095528.

Abstract

In recent years, aldehyde-appended fluorescence probes have attracted increasing attention. Fluorescent biological imaging includes many modern applications for cell and tissue imaging in biomedical research. Meanwhile, the nucleophilic mechanism is a very simple and convenient procedure for the preparation of aldehyde-sensing probes. This tutorial review focuses on aldehyde-bearing chemosensors based on nucleophilic addition mechanism with biological applications.

Keywords: Aldehyde-bearing; biological applications; cell and tissue imaging; fluorescence probes; nucleophilic mechanism; sensing mechanisms..

Publication types

  • Review

MeSH terms

  • Aldehydes / analysis*
  • Aldehydes / chemistry*
  • Biomedical Research
  • Fluorescent Dyes / analysis*
  • Fluorescent Dyes / chemistry
  • Humans
  • Molecular Imaging / methods
  • Molecular Imaging / trends*
  • Optical Imaging / methods
  • Optical Imaging / trends*
  • Spectrometry, Fluorescence

Substances

  • Aldehydes
  • Fluorescent Dyes