Recent trends of nanomedicinal approaches in clinics

Int J Pharm. 2018 Mar 1;538(1-2):263-278. doi: 10.1016/j.ijpharm.2018.01.016. Epub 2018 Jan 12.

Abstract

Nanotechnology has become the indispensable cutting edge science providing solutions to many problems associated with human being. The application of nanotechnology associated to human health "nanomedicine" has revolutionized the drug delivery system by providing improved pharmacological and therapeutic properties of drugs. These advantageous effects of drug loaded nanocarrier systems are embraced by the pharmaceutical industries for the development of different effective nanocarriers. Currently, several drug loaded nanoformulations are approved by the Food and Drug Administration (FDA), and some of them are undergoing clinical trials for the human use. In this review, we have discussed the progress achieved so far for various drug loaded nanoformulations along with few emerging nanoformulations that are about to enter into clinical trials.

Keywords: Clinical trials; Drug delivery; Nanomedicine; Nanoparticles; Nanotechnology; Sustained release.

Publication types

  • Review

MeSH terms

  • Animals
  • Chemistry, Pharmaceutical / methods
  • Drug Approval
  • Drug Carriers / chemistry
  • Drug Delivery Systems*
  • Humans
  • Nanomedicine / methods
  • Nanoparticles*
  • Nanotechnology / methods*
  • Pharmaceutical Preparations / administration & dosage
  • Pharmaceutical Preparations / chemistry

Substances

  • Drug Carriers
  • Pharmaceutical Preparations