Risk Factors of Intrauterine Adhesion after Hysteroscopic Resection of Endometrial Polyps

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2017 Dec 20;39(6):812-816. doi: 10.3881/j.issn.1000-503X.2017.06.013.

Abstract

Objective To analyze the risk factors of intrauterine adhesion (IUA) after hysteroscopic resection of endometrial polyps. Methods Totally 359 patients undergoing hysteroscopic resection of endometrial polyps from January 2013 to December 2016 were enrolled in this study. The clinical data of IUA group and non-IUA group were compared. Univariate analysis was performed to identify the risk factors of IUA,and multivariate Logistic regression analysis was further performed to get the independent risk factors. Results Of these 359 patients,IUA occured after operation in 56 patients (15.60%). Univariate analysis showed underlying diseases (χ2=7.381,P=0.004),multiple polyps (χ2=3.376,P=0.040),uterus with uterine fibroids or endometrial hyperplasia (χ2=6.495,P=0.009),history of curettage(χ2=31.576,P=0.000),pelvic infection (χ2=8.582,P=0.001),intrauterine device (χ2=7.161,P=0.006),history of cesarean section (χ2=5.493,P=0.014),and multigravida were (χ2=16.886,P=0.000) the risk factors of IUA. Logistic regression analysis showed other diseases of uterus(χ2=19.542,P=0.026),history of curettage (χ2=29.614,P=0.000),pelvic infection (χ2=5.627,P=0.002),intrauterine device (χ2=11.342,P=0.08),history of cesarean section(χ2=8.549,P=0.035),and multigravida (χ2=15.493,P=0.000) were the independent risk factors of IUA after hysteroscopic resection of endometrial polyps. Conclusion Other diseases of uterus,history of curettage,pelvic infection,intrauterine device,history of cesarean section,and/or multigravida can increase the risk of IUA after hysteroscopic resection of endometrial polyps.

目的 分析子宫内膜息肉宫腔镜切除术后发生宫腔黏连的相关因素。方法选取2013年1月至2016年12月本院行子宫内膜息肉宫腔镜切除术治疗患者359例,将宫腔黏连组和未发生宫腔黏连组临床资料进行对比分析,找出单因素检验结果存在差异的因素,将此类因素进行多因素Logistic回归分析,最终得出子宫内膜息肉宫腔镜切除术患者发生宫腔黏连的独立危险因素。结果 359例行子宫内膜息肉宫腔镜切除术的患者,其中术后发生宫腔黏连的患者为56例(15.60%)。单因素分析显示,宫腔黏连组患者合并基础疾病(χ2=7.381,P=0.004)、多发息肉患者(χ2=3.376,P=0.040)、子宫合并子宫肌瘤或内膜增生(χ2=6.495,P=0.009)、有刮宫史(χ2=31.576,P=0.000)、有盆腔炎(χ2=8.582,P=0.001)、宫内有节育器(χ2=7.161,P=0.006)、有剖腹产史(χ2=5.493,P=0.014)和孕次≥2(χ2=16.886,P=0.000)的患者比例均高于未发生宫腔黏连组。Logistic回归分析显示子宫合并其他疾病(χ2=19.542,P=0.026)、刮宫史(χ2=29.614,P=0.000)、盆腔炎(χ2=5.627,P=0.002)、宫内有节育器(χ2=11.342,P=0.08)、剖腹产史(χ2=8.549,P=0.035)和孕次(χ2=15.493,P=0.000)为影响子宫内膜息肉宫腔镜切除术患者发生宫腔黏连的独立危险因素。结论 子宫合并其他疾病、有刮宫史、合并盆腔炎、宫内有节育器、剖腹产和多孕次均可能与子宫内膜息肉宫腔镜切除术患者发生宫腔黏连相关联。.

MeSH terms

  • Cesarean Section
  • Female
  • Humans
  • Hysteroscopy
  • Leiomyoma
  • Polyps
  • Pregnancy
  • Risk Factors
  • Tissue Adhesions
  • Uterine Diseases*
  • Uterine Neoplasms