Longitudinal determinants of depression among World Trade Center Health Registry enrollees, 14-15 years after the 9/11 attacks

J Affect Disord. 2018 Mar 15:229:483-490. doi: 10.1016/j.jad.2017.12.105. Epub 2018 Jan 3.

Abstract

Background: Exposure to the September 11, 2001 (9/11) terrorist attacks has been found to be associated with posttraumatic stress disorder (PTSD) and comorbid PTSD and depression up to 10-11 years post-disaster. However, little is known about the longitudinal predictors of mental health conditions over time.

Methods: We examined longitudinal determinants of depression within strata of PTSD among 21,258 enrollees of the World Trade Center Health Registry who completed four questionnaires over 14 years of follow-up (Wave 1 in 2003-04; Wave 2 in 2005-06; Wave 3 in 2011-12; and Wave 4 in 2015-16). PTSD status was measured using the PTSD checklist on all four waves and defined as a score of ≥ 44; depression was assessed using the 8-item Patient Health Questionnaire at Waves 3 and 4 and defined as a score of ≥ 10.

Results: Across Waves 3 and 4, 18.6% experienced depression, and it was more common among those who ever had PTSD (56.1%) compared with those who had not (5.6%). Across PTSD strata, predictors of depression included low income, unemployment, low social integration and support, post-9/11 traumatic life events, and chronic physical illness. These factors also decreased the likelihood of recovering from depression.

Limitations: Depression symptoms were not measured at Waves 1 and 2; data was self-reported.

Conclusions: These findings highlight the substantial burden of depression in a trauma-exposed population 14-15 years post-disaster, especially among those with PTSD. Similar life stressors predicted the course of depression among those with and without PTSD which may inform public health and clinical interventions.

Keywords: Comorbidity; Depression; Disasters; Posttraumatic stress disorder; September 11 terrorist attacks.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Chronic Disease
  • Comorbidity
  • Depression / psychology*
  • Depressive Disorder / psychology*
  • Disasters*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Mental Health
  • Middle Aged
  • Registries
  • Self Report
  • September 11 Terrorist Attacks / psychology*
  • Stress Disorders, Post-Traumatic / psychology*
  • Surveys and Questionnaires
  • Unemployment