A cyanine-based fluorescent cassette with aggregation-induced emission for sensitive detection of pH changes in live cells

Chem Commun (Camb). 2018 Jan 25;54(9):1133-1136. doi: 10.1039/c7cc08986d.

Abstract

An aggregation-induced emission (AIE) cyanine-based fluorescent cassette with a large pseudo-Stokes shift was designed and prepared to sensitively image pH changes in live cells via through-bond energy transfer (TBET) from a tetraphenylethene (TPE) donor to a cyanine acceptor.

MeSH terms

  • Carbocyanines / chemical synthesis
  • Carbocyanines / chemistry*
  • Cell Survival
  • Energy Transfer
  • Ethylenes / chemistry
  • Fluorescent Dyes / chemical synthesis
  • Fluorescent Dyes / chemistry*
  • HeLa Cells
  • Humans
  • Hydrogen-Ion Concentration
  • Molecular Structure
  • Quantum Theory
  • Spectrometry, Fluorescence

Substances

  • Carbocyanines
  • Ethylenes
  • Fluorescent Dyes