Data of expression status of miR- 29a and its putative target mitochondrial apoptosis regulatory gene DRP1 upon miR-15a and miR-214 inhibition

Muhammad Ishtiaq Jan; Riaz Anwar Khan; Abdul Malik; Tahir Ali; Muhammad Bilal; Long Bo; Abdul Sajid; Naseeb Urehman; Nayyar Waseem; Javed Nawab; Murad Ali; Abdul Majeed; Hamid Ahmad; Sohail Aslam; Sadia Hamera; Aneesa Sultan; Mariam Aneesa; Qamar Javed; Iram Murtaza

doi:10.1016/j.dib.2017.12.040

Data of expression status of miR- 29a and its putative target mitochondrial apoptosis regulatory gene DRP1 upon miR-15a and miR-214 inhibition

Data Brief. 2017 Dec 20:16:1000-1004. doi: 10.1016/j.dib.2017.12.040. eCollection 2018 Feb.

Authors

Muhammad Ishtiaq Jan¹, Riaz Anwar Khan², Abdul Malik², Tahir Ali¹, Muhammad Bilal³, Long Bo⁴, Abdul Sajid³, Naseeb Urehman², Nayyar Waseem², Javed Nawab², Murad Ali², Abdul Majeed², Hamid Ahmad², Sohail Aslam², Sadia Hamera⁵, Aneesa Sultan¹, Mariam Aneesa¹, Qamar Javed^{1

6}, Iram Murtaza¹

Affiliations

¹ Signal Transduction Lab, Department of Bio-Chemistry, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad, Islamabad, Pakistan.
² Department of Cardiovascular Surgery, Lady Reading Hospital Peshawar, Pakistan.
³ Livestock and Dairy Development, Veterinary Research Institute, Peshawar, Pakistan.
⁴ Peking Union medical College, Beijing, China.
⁵ LUMS, Department of Biology, SBASSE, Lahore, Pakistan.
⁶ PINST Department, Preston University, Islamabad, Pakistan.

Abstract

Data is about the mitochondrial apoptosis regulatory framework genes PUMA, DRP1 (apoptotic), and ARC (anti-apoptotic) analysis after the employment of their controlling miRNAs inhibitors. The data represents putative conserved targeting of seed regions of miR-15a, miR-29a, and miR-214 with respective target genes PUMA, DRP1, and ARC. Data is of cross interference in expression levels of one miRNA family, miR-29a and its putative target DRP1 upon the inhibitory treatment of other miRNAs 15a and 214.

Keywords: Apoptosis; DRP1; miR-15a; miRNAs inhibition.